Organocatalytic Asymmetric Annulation of 1,3-Bis(alkoxycarbonyl)buta-1,3-dienes and Aldehydes

Pezzati, Bernardo; Chellat, Mathieu; Murphy, John J.; Besnard, Céline; Reginato, Gianna; Stephens, John C.; Alexakis, Alexandre

doi:10.1021/ol401042b

Scientific article

English

Organocatalytic Asymmetric Annulation of 1,3-Bis(alkoxycarbonyl)buta-1,3-dienes and Aldehydes

ContributorsPezzati, Bernardo; Chellat, Mathieu; Murphy, John J.; Besnard, Céline; Reginato, Gianna; Stephens, John C.; Alexakis, Alexandre

Published inOrganic letters, vol. 15, no. 12, p. 2950-2953

Publication date2013

Abstract

Asymmetric organocatalytic annulation of E/Z isomeric mixtures of bis(alkyl carboxylate)buta-1,3-dienes and aldehydes has been realized via enamine catalysis. In the presence of α,α-diphenyl-2-pyrrolidinemethanol trimethylsilyl ether, excellent stereo- and enantioselectivities were achieved for a broad spectrum of substrates.

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

PEZZATI, Bernardo et al. Organocatalytic Asymmetric Annulation of 1,3-Bis(alkoxycarbonyl)buta-1,3-dienes and Aldehydes. In: Organic letters, 2013, vol. 15, n° 12, p. 2950–2953. doi: 10.1021/ol401042b

Article (Published version)

Identifiers

PID : unige:28702
DOI : 10.1021/ol401042b

ISSN of the journal1523-7052

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Organocatalytic Asymmetric Annulation of 1,3-Bis(alkoxycarbonyl)buta-1,3-dienes and Aldehydes

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