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Scientific article
English

A carcinoma showing thymus-like elements of the thyroid arising in close association with solid cell nests: evidence for a precursor lesion?

Contributors

Yerly, Stéphane David; Lobrinus, Johannes Alexander; Bongiovanni, Massimo; Becker, Minerva; Zare, Maryam; Granger, Perrine; Pusztaszeri, Marc

Published in

Thyroid, vol. 23, no. 4, p. 511-516

Publication date

2013

Abstract

Carcinoma showing thymus-like elements (CASTLE) is a rare malignant neoplasm of the thyroid gland, morphologically and immunohistologically similar to a thymic carcinoma, whose histogenesis is still debated. Hypotheses include an origin from ectopic thymic tissue, vestige of the thymopharyngeal duct, or branchial pouch remnants from which solid cell nests (SC-nests) originate. The diagnosis of CASTLE may be treacherous due to its rarity and its propensity to mimic other poorly differentiated tumors such as squamous cell carcinoma.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

YERLY, Stéphane David et al. A carcinoma showing thymus-like elements of the thyroid arising in close association with solid cell nests: evidence for a precursor lesion? In: Thyroid, 2013, vol. 23, n° 4, p. 511–516. doi: 10.1089/thy.2011.0415

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1050-7256
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Technical informations

Creation

29/05/2013 10:48:00

First validation

29/05/2013 10:48:00

Update

14/03/2023 20:18:47

Status update

14/03/2023 20:18:47

Last indexation

30/10/2024 09:40:17
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