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Primary pulmonary malignant meningioma with lymph node and liver metastasis in a centenary woman, an autopsy case

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Published in Virchows Archiv. 2013, vol. 462, no. 4, p. 481-5
Abstract Primary meningiomas arising outside the central nervous system are very rare. They have been reported in the head and neck region, in the thorax, the retroperitoneum, and the pelvis. Usually, they behave as slow-growing tumors with a good prognosis. Herein, we report an autopsy case of a 108-year-old woman, known for a right-sided slowly growing lung nodule for 39 years. Death was attributed to cachexia. At post-mortem, a 15-cm mass was present in the right inferior lobe of the lung, associated with an ipsilateral hilar lymphadenopathy, and another 10-cm mass in the liver. Histology revealed a WHO grade III meningioma. No tumor was observed in the cranial cavity. This case illustrates a rare location of meningioma and highlights its biological behavior, with a very slow progression from a most probably benign tumor to a malignant lesion with metastasis over four decades.
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PMID: 23443940
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Article (Published version) (441 Kb) - document accessible for UNIGE members only Limited access to UNIGE
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Research groups Groupe Pache Jean-Claude (pathologie clinique) (658)
Médecine et soins palliatifs (709)
Groupe Jean-Michel Gaspoz (23)
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WEBER, Catherine Marie N. et al. Primary pulmonary malignant meningioma with lymph node and liver metastasis in a centenary woman, an autopsy case. In: Virchows Archiv, 2013, vol. 462, n° 4, p. 481-5. https://archive-ouverte.unige.ch/unige:28597

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Deposited on : 2013-06-17

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