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Title

Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes

Authors
Tran, C.
Juan, L.
Published in Diabetes & Metabolism. 2012
Abstract AIM: Hypothermia is a recognized complication of severe hypoglycaemia, but its prevalence and characteristics are poorly studied. For this reason, this study aimed to evaluate hypothermia in severely hypoglycaemic patients. METHODS: A retrospective chart review was performed including all patients discharged between 2007 and 2010 from the Emergency Department of the Geneva University Hospital with a diagnosis of severe hypoglycaemia. RESULTS: Hypothermia was identified in 30 (23.4%) out of 128 patients with severe hypoglycaemia. Its incidence was not affected by age, type of diabetes, season or time of day (day/night). Using linear regression, the lowest recorded temperature was associated with the Glasgow Coma Scale (GCS) score (r2=13.8%, P<0.0001) and inversely associated with the leukocyte count (r2=13.1%, P=0.001). CONCLUSION: Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes. The associations between hypothermia and the GCS score and the leukocyte count suggest that it is a marker of hypoglycaemia severity and/or duration. Hypothermia may represent an important compensatory mechanism in severe hypoglycaemia, reflecting a decrease in energy demand during glucose deprivation.
Identifiers
PMID: 22559928
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Other version: http://www.sciencedirect.com/science/journal/12623636/38
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Research group Diabète et régulation des gènes (36)
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(ISO format)
TRAN, C. et al. Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes. In: Diabetes & Metabolism, 2012. https://archive-ouverte.unige.ch/unige:28202

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Deposited on : 2013-05-28

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