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Scientific article
German

Prävalenz der Demenz in der Stadt Zürich

Contributors

Gostynski, M.; Ajdacic-Gross, V.; Gutzwiller, F.; Michel, Jean-Pierre; Herrmann, François

Published in

Sozial- und Präventivmedizin, vol. 47, p. 330-335

Publication date

2002

Abstract

Objectives: The purpose of the study was to estimate the prevalence rate of dementia (PRD) in relation to age, gender, and ApoE-genotype. Methods: The random sample consisted of 465 subjects aged 65 and more. The interview was conducted by means of the Canberra Interview for the Elderly. The genotyping of ApoE has been performed by a combination of the polymerase chain reaction and a gel electrophoresis separation. Results: The overall PRD amounted to 10.1 % (95 %CI 6.8-13.3 %) and was higher among females (12.2 %) than among males (4.9 %). The gender difference was of borderline statistical significance (OR 2.17; 95 %CI 0.97-4.84 adjusted for age, education level). PRD rose significantly with age. In contrast, the possession of one copy of ApoE-‹varepsilon›4-allele was not associated with a higher risk of having dementia (OR 1.48; 95 %CI 0.60-3.63 adjusted for age, gender, education level). Conclusions: These results are consistent with the finding from other authors.

Keywords

  • Dementia
  • Elderly
  • Prevalence
  • Epidemiology

UNIGE affiliation entities

Citation (ISO format)

GOSTYNSKI, M. et al. Prävalenz der Demenz in der Stadt Zürich. In: Sozial- und Präventivmedizin, 2002, vol. 47, p. 330–335.

Main files (1)

Article

Identifiers

  • PID : unige:28102

Journal ISSN

0303-8408
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Technical informations

Creation

28/05/2013 15:43:02

First validation

28/05/2013 15:43:02

Update

14/03/2023 20:16:28

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