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Title

Detection of ATP by "in line" 31P magnetic resonance spectroscopy during oxygenated hypothermic pulsatile perfusion of pigs' kidneys

Authors
Hergt, Martin
Nastasi, Antonio
Ruttimann, Raphael
Published in Magma: Magnetic Resonance Materials in Physics, Biology and Medicine. 2012, vol. 25, no. 5, p. 391-9
Abstract To demonstrate that adenosine triphosphate (ATP), which provides a valuable biomarker for kidney viability in the context of donation after cardiac death (DCD) transplantation, can be detected by means of (31)P magnetic resonance spectroscopy (MRS) if kidneys are perfused with oxygenated hypothermic pulsatile perfusion (O(2)+HPP).
Keywords Adenosine Triphosphate/analysis/chemistryAnimalsCell SurvivalDeathEquipment DesignIschemia/pathologyKidney/metabolismKidney Transplantation/methodsMagnetic Resonance Imaging/methodsMagnetic Resonance Spectroscopy/methodsOrgan Preservation/methodsOxygen/chemistryPhosphorus Isotopes/pharmacologyPulsatile FlowSwineTime Factors
Identifiers
PMID: 22644411
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Structures
Research groups Chirurgie viscérale (104)
Imagerie cardiaque fonctionnelle (541)
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(ISO format)
LAZEYRAS, François et al. Detection of ATP by "in line" 31P magnetic resonance spectroscopy during oxygenated hypothermic pulsatile perfusion of pigs' kidneys. In: Magma: Magnetic Resonance Materials in Physics, Biology and Medicine, 2012, vol. 25, n° 5, p. 391-9. https://archive-ouverte.unige.ch/unige:27971

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Deposited on : 2013-05-24

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