Erythrocytapheresis and sublingual micro-vascular flow in severe malaria
|Published in||Clinical Hemorheology and Microcirculation. 2010, vol. 46, no. 4, p. 299-304|
|Abstract||The authors describe clinical cases of two patients admitted to intensive care unit following severe Plasmodium falciparum malaria. Patients' sublingual microcirculation was monitored by on-line Sidestream dark-field imaging before and after treatment with erythrocytapheresis. Before treatment, microcirculatory flow alterations were obvious. Therapy produced a rapid decrease in infected red blood cells with a significant improvement in microcirculatory flows, capillary perfusion and patients' outcome. The present cases emphasize the relevance of microcirculation monitoring in patients with capillary perfusion alterations resulting from severe malaria. As far as we know, this is the first observations of an improvement of capillary perfusion after erythrocytapheresis.|
|Keywords||Aged, 80 and over — Blood Component Removal — Capillaries/physiology — Erythrocyte Transfusion — Female — Humans — Malaria, Falciparum/physiopathology/therapy — Male — Microcirculation — Middle Aged — Mouth Floor/blood supply — Parasitemia/therapy|
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|Research group||Groupe de Recherche en Hémodynamique (913)|
|SIEGENTHALER, Nils, GIRAUD, Raphaël, BENDJELID, Karim. Erythrocytapheresis and sublingual micro-vascular flow in severe malaria. In: Clinical Hemorheology and Microcirculation, 2010, vol. 46, n° 4, p. 299-304. https://archive-ouverte.unige.ch/unige:27951|