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Transplantation rénale ABO incompatible

Published in Revue médicale suisse. 2012, vol. 8, no. 346, p. 1310-3
Abstract ABO-incompatible living donor renal transplantation began in 1982. It may provide a significant source of organs. One dose of rituximab is given four weeks pre-operatively and oral triple immunosuppressive regimen is introduced 7 days pre-operatively. Anti A/B titres are lowered to less than 1:8 by specific immunoadsorption with Glycosorb column. During the first 15 days post-transplant, accommodation state is acquired. Thereafter, graft and patient survivals, and acute humoral rejection rates are the same as those of ABO identical renal transplantations.
Keywords ABO Blood-Group System/immunologyAdaptation, Physiological/immunology/physiologyAntibodies/bloodBlood Group Incompatibility/blood/immunologyEuropeHealth Plan Implementation/methodsHumansKidney Transplantation/immunologyLiving DonorsSwitzerlandTransplantation Conditioning/methods
PMID: 22792594
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Other version: http://rms.medhyg.ch/numero-346-page-1310.htm
Research groups Hépatologie chirurgicale (327)
Groupe Pierre-Yves Martin (néphrologie) (30)
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HADAYA, Karine. Transplantation rénale ABO incompatible. In: Revue médicale suisse, 2012, vol. 8, n° 346, p. 1310-3. https://archive-ouverte.unige.ch/unige:27871

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Deposited on : 2013-05-15

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