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Potential of T-regulatory cells to protect xenografts

Golshayan, Déla
Published in Current Opinion in Organ Transplantation. 2012, vol. 17, no. 2, p. 155-61
Abstract Immunological barriers still preclude clinical xenotransplantation. The protective role of CD4(+)CD25(+)Foxp3(+) T-regulatory cells (Treg) in allotransplantation is well described and, therefore, could represent a promising therapeutical tool for xenotransplantation. This review addresses the latest findings on Treg in xenotransplantation research.
Keywords AnimalsAntibodies, Monoclonal/immunology/pharmacologyEndothelium, Vascular/immunologyHumansImmunity, Cellular/drug effects/immunologyImmunosuppressive Agents/pharmacologyInterleukin-10/immunologySirolimus/pharmacologySwineT-Lymphocytes, Regulatory/drug effects/immunologyTransplantation, Heterologous/immunology
PMID: 22273594
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Article (Published version) (440 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Cultures cellulaires et transplantations (519)
Groupe Seebach Jorg Dieter (transplantation et immunologie) (856)
(ISO format)
MULLER, Yannick et al. Potential of T-regulatory cells to protect xenografts. In: Current Opinion in Organ Transplantation, 2012, vol. 17, n° 2, p. 155-61. doi: 10.1097/MOT.0b013e3283508e17 https://archive-ouverte.unige.ch/unige:27645

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Deposited on : 2013-05-02

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