en
Scientific article
English

Autoantibodies against apolipoprotein A-1 and phosphorylcholine for diagnosis of non-ST-segment elevation myocardial infarction

Published inJournal of internal medicine, vol. 271, no. 5, p. 451-462
Publication date2012
Abstract

To explore the diagnostic accuracies of anti-apolipoproteinA-1 (anti-ApoA-1) IgG and anti-phosphorylcholine (anti-PC) IgM alone, expressed as a ratio (anti-ApoA-1 IgG/anti-PC IgM), and combined with the Thrombolysis In Myocardial Infarction (TIMI) score for non-ST-segment elevation myocardial infarction (NSTEMI) (NSTEMI-TIMI score) to create a new diagnostic algorithm - the Clinical Autoantibody Ratio (CABR) score - for the diagnosis of NSTEMI and subsequent cardiac troponin I (cTnI) elevation in patients with acute chest pain (ACP).

Keywords
  • Aged
  • Algorithms
  • Apolipoprotein A-I/immunology
  • Area Under Curve
  • Autoantibodies/blood
  • Confidence Intervals
  • Electrocardiography/methods
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G/blood
  • Immunoglobulin M/blood
  • Male
  • Middle Aged
  • Myocardial Infarction/diagnosis/drug therapy/immunology
  • Odds Ratio
  • Phosphorylcholine/immunology
  • Predictive Value of Tests
  • Thrombolytic Therapy/methods
Citation (ISO format)
KELLER, P.-F. et al. Autoantibodies against apolipoprotein A-1 and phosphorylcholine for diagnosis of non-ST-segment elevation myocardial infarction. In: Journal of internal medicine, 2012, vol. 271, n° 5, p. 451–462. doi: 10.1111/j.1365-2796.2011.02479.x
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0954-6820
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