Article (Published version) (327 Kb) - 
Limited access to UNIGEOther version: http://www.intmedpress.com/journals/avt/abstract.cfm?id=2018&pid=48
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Scientific Article
unige:27573 
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The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients |
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| Published in | Antiviral Therapy. 2012, vol. 17, no. 3, p. 541-7 | |
| Abstract | Chronic hepatitis C infection is a major cause of end-stage liver disease. Therapy outcome is influenced by 25-OH vitamin D deficiency. To further address this observation, our study investigates the impact of the vitamin D receptor (NR1I1) haplotype and combined effects of plasma vitamin D levels in a well-described cohort of hepatitis C patients. | |
| Keywords | Adult — Aged — Antiviral Agents/therapeutic use — Cohort Studies — Drug Therapy, Combination — Female — Genotype — Haplotypes/genetics — Hepacivirus/drug effects/genetics — Hepatitis C, Chronic/drug therapy/genetics/virology — Humans — Interferons/therapeutic use — Male — Middle Aged — Polyethylene Glycols/therapeutic use — Polymorphism, Genetic — Receptors, Calcitriol/genetics — Ribavirin/therapeutic use — Treatment Outcome — Vitamin D/blood | |
| Identifiers | DOI: 10.3851/IMP2018 PMID: 22300961 | |
| Full text |
Article (Published version) (327 Kb) - Limited access to UNIGE Other version: http://www.intmedpress.com/journals/avt/abstract.cfm?id=2018&pid=48 |
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| Structures | ||
| Research groups | Métastases du foie (657) Etudes et traitement de l'hépatite C et B (554) | |
| Citation (ISO format) | BAUR, Katharina et al. The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients. In: Antiviral Therapy, 2012, vol. 17, n° 3, p. 541-7. doi: 10.3851/IMP2018 https://archive-ouverte.unige.ch/unige:27573 |
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