Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

Bezemer, Geert; Van Gool, Arthur R; Verheij-Hart, Elke; Hansen, Bettina E; Lurie, Yoav; Esteban, Juan I; Lagging, Martin; Negro, Francesco; Zeuzem, Stefan; Ferrari, Carlo; Pawlotsky, Jean-Michel; Neumann, Avidan U; Schalm, Solko W; de Knegt, Robert J

doi:10.1186/1471-230X-12-11

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Title		Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study
Authors		Bezemer, Geert Van Gool, Arthur R Verheij-Hart, Elke Hansen, Bettina E Lurie, Yoav Esteban, Juan I Lagging, Martin Negro, Francesco Zeuzem, Stefan Ferrari, Carlo Pawlotsky, Jean-Michel Neumann, Avidan U Schalm, Solko W de Knegt, Robert J show all authors [1 - 14]
Published in		BMC Gastroenterology. 2012, vol. 12, 11
Abstract		Hepatitis C decreases health related quality of life (HRQL) which is further diminished by antiviral therapy. HRQL improves after successful treatment. This trial explores the course of and factors associated with HRQL in patients given individualized or standard treatment based on early treatment response (Ditto-study).
Keywords		Adult — Age Factors — Aged — Antiviral Agents/therapeutic use — Dose-Response Relationship, Drug — Drug Therapy, Combination — Europe — Female — Health Surveys — Hepatitis C, Chronic/drug therapy — Humans — Interferon-alpha/therapeutic use — International Cooperation — Male — Middle Aged — Multivariate Analysis — Polyethylene Glycols/therapeutic use — Quality of Life — Recombinant Proteins/therapeutic use — Ribavirin/therapeutic use — Severity of Illness Index — Sex Characteristics — Treatment Outcome
Identifiers		DOI: 10.1186/1471-230X-12-11 PMID: 22292521
Full text		Article (Published version) (337 Kb) - Free access
Structures		Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Research group		Etudes et traitement de l'hépatite C et B (554)
Citation (ISO format)		BEZEMER, Geert et al. Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study. In: BMC Gastroenterology, 2012, vol. 12, p. 11. doi: 10.1186/1471-230X-12-11 https://archive-ouverte.unige.ch/unige:27535