Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

Bezemer, Geert; Van Gool, Arthur R; Verheij-Hart, Elke; Hansen, Bettina E; Lurie, Yoav; Esteban, Juan I; Lagging, Martin; Negro, Francesco; Zeuzem, Stefan; Ferrari, Carlo; Pawlotsky, Jean-Michel; Neumann, Avidan U; Schalm, Solko W; de Knegt, Robert J

doi:10.1186/1471-230X-12-11

Scientific article

Open access

English

Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

ContributorsBezemer, Geert; Van Gool, Arthur R; Verheij-Hart, Elke; Hansen, Bettina E; Lurie, Yoav; Esteban, Juan I; Lagging, Martin; Negro, Francesco; Zeuzem, Stefan; Ferrari, Carlo; Pawlotsky, Jean-Michel; Neumann, Avidan U; Schalm, Solko W; de Knegt, Robert J

Published inBMC gastroenterology, vol. 12, 11

Publication date2012

Abstract

Hepatitis C decreases health related quality of life (HRQL) which is further diminished by antiviral therapy. HRQL improves after successful treatment. This trial explores the course of and factors associated with HRQL in patients given individualized or standard treatment based on early treatment response (Ditto-study).

Keywords

Adult
Age Factors
Aged
Antiviral Agents/therapeutic use
Dose-Response Relationship, Drug
Drug Therapy, Combination
Europe
Female
Health Surveys
Hepatitis C, Chronic/drug therapy
Humans
Interferon-alpha/therapeutic use
International Cooperation
Male
Middle Aged
Multivariate Analysis
Polyethylene Glycols/therapeutic use
Quality of Life
Recombinant Proteins/therapeutic use
Ribavirin/therapeutic use
Severity of Illness Index
Sex Characteristics
Treatment Outcome

Affiliation

Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie

Research group

Etudes et traitement de l'hépatite C et B (554)

Citation (ISO format)

BEZEMER, Geert et al. Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study. In: BMC gastroenterology, 2012, vol. 12, p. 11. doi: 10.1186/1471-230X-12-11

Article (Published version)

CC BY

Identifiers

PID : unige:27535
DOI : 10.1186/1471-230X-12-11
PMID : 22292521

ISSN of the journal1471-230X

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Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study

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