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A survival analysis of the liver-first reversed management of advanced simultaneous colorectal liver metastases: a LiverMetSurvey-based study

Published inAnnals of surgery, vol. 256, no. 5, p. 772-778;discussion778-9
Publication date2012
Abstract

Liver-first reversed management (RM) for the treatment of patients with simultaneous colorectal liver metastases (CRLM) includes liver-directed chemotherapy, the resection of the CRLM, and the subsequent resection of the primary cancer. Retrospective data have shown that up to 80% of patients can successfully undergo a complete RM, whereas less than 30% of those undergoing classical management (CM) do so. This registry-based study compared the 2 approaches.

Keywords
  • Antineoplastic Combined Chemotherapy Protocols/therapeutic use
  • Camptothecin/administration & dosage/analogs & derivatives
  • Chi-Square Distribution
  • Colorectal Neoplasms/drug therapy/pathology/surgery
  • Combined Modality Therapy
  • Female
  • Humans
  • Liver Neoplasms/drug therapy/secondary/surgery
  • Logistic Models
  • Male
  • Middle Aged
  • Organoplatinum Compounds/administration & dosage
  • Propensity Score
  • Proportional Hazards Models
  • Registries
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome
Citation (ISO format)
ANDRES, Axel et al. A survival analysis of the liver-first reversed management of advanced simultaneous colorectal liver metastases: a LiverMetSurvey-based study. In: Annals of surgery, 2012, vol. 256, n° 5, p. 772–778;discussion778–9. doi: 10.1097/SLA.0b013e3182734423
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Article (Published version)
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Identifiers
ISSN of the journal0003-4932
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