Bicyclonucleosides and ring-chain interconversion

Tronchet, Jean Marcel Julien; Zsely Schaffter, Martina Maria; Brenas-Chinchon, Laetitia; Lassout, Olivier; Grand, Eric; Seuret, Patrick; Grigorov, Martin; Rivara-Minten, Elisabeth; Geoffroy, Michel

doi:10.1080/15257779908041651

Scientific article

English

Bicyclonucleosides and ring-chain interconversion

ContributorsTronchet, Jean Marcel Julien; Zsely Schaffter, Martina Maria; Brenas-Chinchon, Laetitia; Lassout, Olivier; Grand, Eric; Seuret, Patrick; Grigorov, Martin; Rivara-Minten, Elisabeth; Geoffroy, Michel

Published inNucleosides & nucleotides, vol. 18, no. 4-5, p. 1077-1078

Publication date1999

Abstract

Four types of bicyclonucleosides differing in the easiness of their ring-chain interconversion have been prepared, some exhibited anti-HIV activity and the ratio of their cyclic and open-chain forms could have some bearing on their biological activity.

Keywords

Drug design & development
Medicinal & pharmaceutical chemistry
Organic chemistry
Pharmaceutical science

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie physique

Research group

Groupe Geoffroy

Citation (ISO format)

TRONCHET, Jean Marcel Julien et al. Bicyclonucleosides and ring-chain interconversion. In: Nucleosides & nucleotides, 1999, vol. 18, n° 4-5, p. 1077–1078. doi: 10.1080/15257779908041651

Identifiers

PID : unige:2749
DOI : 10.1080/15257779908041651
PMID : 10432742

ISSN of the journal0732-8311

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Bicyclonucleosides and ring-chain interconversion

Four types of bicyclonucleosides differing in the easiness of their ring-chain interconversion have been prepared, some exhibited anti-HIV activity and the ratio of their cyclic and open-chain forms could have some bearing on their biological activity.

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