en
Scientific article
Open access
English

Spin labeled hydroxyproline analogues

Published inIl Farmaco, vol. 54, no. 4, p. 637-641
Publication date1999
Abstract

The synthesis and properties of both epimers of 4-(N-hydroxyamino)-N-tosyl-Image -proline methyl ester and derivatives thereof are reported. In the presence of air, the compounds bearing a free N-hydroxyamino group oxidized in solution to give the corresponding aminoxyl free radicals, EPR spectra of which were Recorded. None of these compounds showed any interesting biological activity as such, but they constitute potential synthetic building blocks towards spin labeled glycopeptide or oligopeptide analogues.

Keywords
  • L-Proline
  • N-hydroxyamino
  • EPR spectroscopy
  • Aminoxyls
Research group
Citation (ISO format)
TRONCHET, Jean Marcel Julien et al. Spin labeled hydroxyproline analogues. In: Il Farmaco, 1999, vol. 54, n° 4, p. 637–641. doi: 10.1016/S0014-827X(99)00083-X
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Article (Published version)
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Identifiers
ISSN of the journal0014-827X
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Technical informations

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