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Scientific article
Open access
English

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C

Published inPloS one, vol. 7, no. 7, e40159
Publication date2012
Abstract

To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.

Keywords
  • 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics
  • Adult
  • Aged
  • Calcifediol/blood
  • Demography
  • Female
  • Gene Frequency/genetics
  • Hepatitis C, Chronic/blood/drug therapy/genetics/virology
  • Humans
  • Interferon-alpha/therapeutic use
  • Interleukins/genetics
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide/genetics
  • Reproducibility of Results
  • Ribavirin/therapeutic use
  • Seasons
  • Treatment Outcome
  • Vitamin D/blood/metabolism
  • Young Adult
Citation (ISO format)
LANGE, Christian M et al. A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C. In: PloS one, 2012, vol. 7, n° 7, p. e40159. doi: 10.1371/journal.pone.0040159
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal1932-6203
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325downloads

Technical informations

Creation03/25/2013 3:34:00 PM
First validation03/25/2013 3:34:00 PM
Update time03/14/2023 8:07:06 PM
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