Scientific article
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C
ContributorsLange, Christian M; Bibert, Stéphanie; Kutalik, Zoltan; Burgisser, Philippe; Cerny, Andreas; Dufour, Jean-François Jacques; Geier, Andreas; Gerlach, Tilman Joern; Heim, Markus H; Malinverni, Raffaele; Negro, Francesco; Regenass, Stephan; Badenhoop, Klaus; Bojunga, Jörg; Sarrazin, Christoph; Zeuzem, Stefan; Müller, Tobias; Berg, Thomas; Bochud, Pierre-Yves; Moradpour, Darius
Published inPloS one, vol. 7, no. 7, e40159
Publication date2012
Abstract
Keywords
- 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics
- Adult
- Aged
- Calcifediol/blood
- Demography
- Female
- Gene Frequency/genetics
- Hepatitis C, Chronic/blood/drug therapy/genetics/virology
- Humans
- Interferon-alpha/therapeutic use
- Interleukins/genetics
- Male
- Middle Aged
- Polymorphism, Single Nucleotide/genetics
- Reproducibility of Results
- Ribavirin/therapeutic use
- Seasons
- Treatment Outcome
- Vitamin D/blood/metabolism
- Young Adult
Research groups
Citation (ISO format)
LANGE, Christian M et al. A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C. In: PloS one, 2012, vol. 7, n° 7, p. e40159. doi: 10.1371/journal.pone.0040159
Main files (1)
Article (Published version)
Identifiers
- PID : unige:27166
- DOI : 10.1371/journal.pone.0040159
- PMID : 22808108
Journal ISSN1932-6203
