UNIGE document Scientific Article
previous document  unige:27046  next document
add to browser collection
Title

Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia

Authors
Published in Critical Care Medicine. 2004, vol. 32, no. 8, p. 1759-63
Abstract Infection of pancreatic necrosis is a severe complication of acute pancreatitis. Because Toll-like receptor 4 (TLR4) has been identified as a receptor necessary to transduct the signal of bacteria-derived lipopolysaccharide into cells, we investigated the role of TLR4 on pancreatic and pulmonary injury in acute pancreatitis and acute pancreatitis associated with endotoxemia in wild-type and TLR4-deficient mice.
Keywords Acute DiseaseAmylases/blood/secretionAnimalsCaeruleinDisease Models, AnimalLipopolysaccharidesLung Diseases/chemically induced/etiology/metabolismMembrane Glycoproteins/metabolismMicePancreas/enzymologyPancreatitis/chemically induced/complications/metabolismReceptors, Cell Surface/metabolismToll-Like Receptor 4Toll-Like Receptors
Identifiers
PMID: 15286555
Full text
Article (Published version) (880 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Physiopathologie de la pancréatite aiguë (601)
Pharmacologie et imagerie du foie (664)
Mucoviscidose et jonctions GAP (229)
Citation
(ISO format)
PASTOR, Catherine et al. Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia. In: Critical Care Medicine, 2004, vol. 32, n° 8, p. 1759-63. https://archive-ouverte.unige.ch/unige:27046

219 hits

1 download

Update

Deposited on : 2013-03-26

Export document
Format :
Citation style :