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Arterial to end-tidal CO(2) pressure gradient: a bedside parameter to monitor patients with massive pulmonary embolism

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Published in The American Journal of Emergency Medicine. 2013, vol. 31, no. 3, p. 639.e1-e3
Abstract Massive pulmonary embolism (PE) is a life-threatening condition that mandates urgent pulmonary reperfusion. To adequately monitor hemodynamic of these highly unstable patients remains challenging because there is no validated correlation between the arterial oxygen level, the severity of the PE, and the efficacy of the adopted reperfusion therapy. We report on 2 patients presenting with massive PE, who were monitored measuring simultaneously the cardiac output and the pressure gradient between arterial and end-tidal CO2. The P(a-ET CO2) has timely suggested the efficacy of the attempted reperfusion treatment. This easily obtainable physiologic gradient provides immediate information on pulmonary blood flow states as well as on ventilatory functions. This noninvasive bedside parameter should be part of the monitoring of mechanically ventilated patients treated for massive PE.
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PMID: 23380099
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Article (Published version) (315 Kb) - document accessible for UNIGE members only Limited access to UNIGE
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Research group Groupe de Recherche en Hémodynamique (913)
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PARK, Chan-Il, BENDJELID, Karim, BONVINI, Robert. Arterial to end-tidal CO(2) pressure gradient: a bedside parameter to monitor patients with massive pulmonary embolism. In: The American Journal of Emergency Medicine, 2013, vol. 31, n° 3, p. 639.e1-e3. https://archive-ouverte.unige.ch/unige:26514

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Deposited on : 2013-03-01

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