Daphnia magna, a host for evaluation of bacterial virulence

Le Coadic, Marion; Simon, Marianne; Marchetti, Anna; Ebert, Dieter; Cosson, Pierre

doi:10.1128/AEM.06278-11

Scientific article

English

Daphnia magna, a host for evaluation of bacterial virulence

ContributorsLe Coadic, Marion; Simon, Marianne; Marchetti, Anna

; Ebert, Dieter; Cosson, Pierre

Published inApplied and environmental microbiology, vol. 78, no. 2, p. 593-595

Publication date2012

Abstract

We show that Daphnia magna can be used to assess acute virulence of pathogens relevant to human health, such as Pseudomonas aeruginosa or Photorhabdus asymbiotica. Analysis of bacterial mutants suggests that P. aeruginosa uses similar mechanisms to infect Daphnia and other hosts.

Keywords

Animals
Daphnia/microbiology
Humans
Photorhabdus/genetics/pathogenicity
Pseudomonas aeruginosa/genetics/pathogenicity
Survival Analysis
Virulence

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme

Research groups

Phagocytose (140)

Citation (ISO format)

LE COADIC, Marion et al. Daphnia magna, a host for evaluation of bacterial virulence. In: Applied and environmental microbiology, 2012, vol. 78, n° 2, p. 593–595. doi: 10.1128/AEM.06278-11

Article (Published version)

Identifiers

PID : unige:26354
DOI : 10.1128/AEM.06278-11
PMID : 22081563

Journal ISSN0099-2240

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Daphnia magna, a host for evaluation of bacterial virulence

We show that Daphnia magna can be used to assess acute virulence of pathogens relevant to human health, such as Pseudomonas aeruginosa or Photorhabdus asymbiotica. Analysis of bacterial mutants suggests that P. aeruginosa uses similar mechanisms to infect Daphnia and other hosts.

Technical informations