The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology

Méan, Marie; Righini, Marc Philip; Jaeger, Kurt; Beer, Hans-Jürg; Frauchiger, Beat; Osterwalder, Josef Johann; Kucher, Nils; Lämmle, Bernhard; Cornuz, Jacques; Angelillo-Scherrer, Anne; Rodondi, Nicolas; Limacher, Andreas; Trelle, Sven; Matter, Christian M; Husmann, Marc; Banyai, Martin; Aschwanden, Markus; Egloff, Michaël; Mazzolai, Lucia; Hugli, Olivier; Bounameaux, Henri; Aujesky, Drahomir

doi:10.1007/s11239-013-0875-2

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Title		The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology
Authors		Méan, Marie Righini, Marc Philip Jaeger, Kurt Beer, Hans-Jürg Frauchiger, Beat Osterwalder, Josef Johann Kucher, Nils Lämmle, Bernhard Cornuz, Jacques Angelillo-Scherrer, Anne Rodondi, Nicolas Limacher, Andreas Trelle, Sven Matter, Christian M Husmann, Marc Banyai, Martin Aschwanden, Markus Egloff, Michaël Mazzolai, Lucia Hugli, Olivier Bounameaux, Henri Aujesky, Drahomir show all authors [1 - 22]
Published in		Journal of Thrombosis and Thrombolysis. 2013, vol. 36, no. 4, p. 475-483
Abstract		Venous thromboembolism (VTE) is common and has a high impact on morbidity, mortality, and costs of care. Although most of the patients with VTE are aged ≥65 years, there is little data about the medical outcomes in the elderly with VTE. The Swiss Cohort of Elderly Patients with VTE (SWITCO65+) is a prospective multicenter cohort study of in- and outpatients aged ≥65 years with acute VTE from all five Swiss university and four high-volume non-university hospitals. The goal is to examine which clinical and biological factors and processes of care drive short- and long-term medical outcomes, health-related quality of life, and medical resource utilization in elderly patients with acute VTE. The cohort also includes a large biobank with biological material from each participant. From September 2009 to March 2012, 1,863 elderly patients with VTE were screened and 1003 (53.8 %) were enrolled in the cohort. Overall, 51.7 % of patients were aged ≥75 years and 52.7 % were men. By October 16, 2012, after an average follow-up time of 512 days, 799 (79.7 %) patients were still actively participating. SWITCO65+ is a unique opportunity to study short- and long-term outcomes in elderly patients with VTE. The Steering Committee encourages national and international collaborative research projects related to SWITCO65+, including sharing anonymized data and biological samples.
Identifiers		DOI: 10.1007/s11239-013-0875-2 PMID: 23359097
Full text		Article (Published version) (254 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires
Research groups		La maladie thromboembolique veineuse (808) Geneva Platelet Group (13)
Citation (ISO format)		MÉAN, Marie et al. The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology. In: Journal of Thrombosis and Thrombolysis, 2013, vol. 36, n° 4, p. 475-483. doi: 10.1007/s11239-013-0875-2 https://archive-ouverte.unige.ch/unige:26320