Scientific article
OA Policy
English

Oral rivaroxaban for the treatment of symptomatic pulmonary embolism

Published in

The New England journal of medicine, vol. 366, no. 14, p. 1287-1297

Publication date

2012

Abstract

A fixed-dose regimen of rivaroxaban, an oral factor Xa inhibitor, has been shown to be as effective as standard anticoagulant therapy for the treatment of deep-vein thrombosis, without the need for laboratory monitoring. This approach may also simplify the treatment of pulmonary embolism.

Keywords

  • Administration
  • Oral
  • Aged
  • Anticoagulants/adverse effects/therapeutic use
  • Drug Therapy
  • Combination
  • Enoxaparin/adverse effects/therapeutic use
  • Female
  • Follow-Up Studies
  • Hemorrhage/chemically induced
  • Humans
  • International Normalized Ratio
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Morpholines/adverse effects/therapeutic use
  • Pulmonary Embolism/drug therapy/mortality
  • Recurrence
  • Thiophenes/adverse effects/therapeutic use
  • Treatment Outcome
  • Vitamin K/antagonists & inhibitors

Citation (ISO format)

BÜLLER, Harry R et al. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. In: The New England journal of medicine, 2012, vol. 366, n° 14, p. 1287–1297. doi: 10.1056/NEJMoa1113572

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0028-4793
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5208downloads

Technical informations

Creation

11/10/2012 09:59:00

First validation

11/10/2012 09:59:00

Update

09/02/2026 14:33:28

Status update

09/02/2026 14:33:28

Last indexation

20/04/2026 15:27:13
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