Diagnostic performance of ethyl glucuronide in hair for the investigation of alcohol drinking behavior: a comparison with traditional biomarkers

Kharbouche, Hicham; Faouzi, Mohamed; Sanchez, Nathalie; Daeppen, Jean Bernard; Augsburger, Marc; Mangin, Patrice; Staub, Christian; Sporkert, Frank

doi:10.1007/s00414-011-0619-9

Scientific article

English

Diagnostic performance of ethyl glucuronide in hair for the investigation of alcohol drinking behavior: a comparison with traditional biomarkers

ContributorsKharbouche, Hicham; Faouzi, Mohamed; Sanchez, Nathalie; Daeppen, Jean Bernard; Augsburger, Marc; Mangin, Patrice; Staub, Christian; Sporkert, Frank

Published inInternational journal of legal medicine, vol. 126, no. 2, p. 243-250

Publication date2012

Abstract

Ethyl glucuronide (EtG) in hair has emerged as a useful biomarker for detecting alcohol abuse and monitoring abstinence. However, there is a need to establish a reliable cutoff value for the detection of chronic and excessive alcohol consumption.

Keywords

Adult
Aged
Alanine Transaminase/analysis
Alcohol Drinking/blood
Alcoholism/blood/diagnosis
Area Under Curve
Aspartate Aminotransferases/isolation & purification
Biological Markers/analysis
Female
Glucuronates/isolation & purification
Hair/chemistry
Humans
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
Substance Abuse Detection/methods
Transferrin/analogs & derivatives/isolation & purification
Young Adult
Gamma-Glutamyltransferase/isolation & purification

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de médecine légale

Research groups

Groupe Mangin Patrice (médecine légale) (862)

Citation (ISO format)

KHARBOUCHE, Hicham et al. Diagnostic performance of ethyl glucuronide in hair for the investigation of alcohol drinking behavior: a comparison with traditional biomarkers. In: International journal of legal medicine, 2012, vol. 126, n° 2, p. 243–250. doi: 10.1007/s00414-011-0619-9

Article (Published version)

Identifiers

PID : unige:26289
DOI : 10.1007/s00414-011-0619-9
PMID : 21910015

Journal ISSN0937-9827

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Diagnostic performance of ethyl glucuronide in hair for the investigation of alcohol drinking behavior: a comparison with traditional biomarkers

Ethyl glucuronide (EtG) in hair has emerged as a useful biomarker for detecting alcohol abuse and monitoring abstinence. However, there is a need to establish a reliable cutoff value for the detection of chronic and excessive alcohol consumption.

Technical informations