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Postmortem chemistry update part I.

Published in International journal of legal medicine. 2012, vol. 126, no. 2, p. 187-98
Collection Open Access - Licence nationale Springer
Abstract Postmortem chemistry is becoming increasingly essential in the forensic pathology routine and considerable progress has been made over the past years. Biochemical analyses of vitreous humor, cerebrospinal fluid, blood and urine may provide significant information in determining the cause of death or in elucidating forensic cases. Postmortem chemistry may essentially contribute in the determination of the cause of death when the pathophysiological changes involved in the death process cannot be detected by morphological methods (e.g. diabetes mellitus, alcoholic ketoacidosis and electrolytic disorders). It can also provide significant information and useful support in other forensic situations, including anaphylaxis, hypothermia, sepsis and hormonal disturbances. In this article, we present a review of the literature that covers this vast topic and we report the results of our observations. We have focused our attention on glucose metabolism, renal function and electrolytic disorders.
Keywords Biological Markers/analysisBodily Secretions/chemistryBody Fluids/chemistryC-Peptide/analysisDiabetes Mellitus/diagnosis/metabolism/pathologyDiabetic Ketoacidosis/diagnosis/metabolism/pathologyElectrolytes/analysisForensic Pathology/methodsFructosamine/analysisGlucose/metabolismHemoglobin AGlycosylated/analysisHumansHyperglycemia/diagnosis/metabolism/pathologyInsulin/analysisKetone Bodies/analysisKidney Function TestsPostmortem Changes
PMID: 21947676
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Article (Published version) (204 Kb) - public document Free access
Research group Groupe Mangin Patrice (médecine légale) (862)
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PALMIERE, Cristian, MANGIN, Patrice. Postmortem chemistry update part I. In: International journal of legal medicine, 2012, vol. 126, n° 2, p. 187-98. doi: 10.1007/s00414-011-0625-y https://archive-ouverte.unige.ch/unige:26284

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Deposited on : 2013-02-07

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