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Treatment with levetiracetam in a patient with pervasive developmental disorders, severe intellectual disability, self-injurious behavior, and seizures: A case report

Published inNeurocase, vol. 18, no. 5, p. 386-391
Publication date2012
Abstract

Pervasive developmental disorder is characterized by various symptoms that often include self-injurious behavior (SIB). Episodes of SIB occur in the context of high emotional arousal, anger, or fear and may be related to epilepsy. We report the case of a 20-year-old man with pervasive developmental disorder presenting with SIB non-responsive to antipsychotic medication. Positron emission tomography showed a right temporoparietal hypometabolic focal lesion suggestive of an epileptic focus. Two weeks after initiation of levetiracetam (Keppra®), SIB disappeared, without recurrence 24 months later. Levetiracetam (Keppra®) may be beneficial for such patients.

Citation (ISO format)
DERIAZ, Nicolas et al. Treatment with levetiracetam in a patient with pervasive developmental disorders, severe intellectual disability, self-injurious behavior, and seizures: A case report. In: Neurocase, 2012, vol. 18, n° 5, p. 386–391. doi: 10.1080/13554794.2011.627336
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Journal ISSN1355-4794
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Creation22/10/2012 19:02:00
First validation22/10/2012 19:02:00
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