UNIGE document Scientific Article
previous document  unige:25868  next document
add to browser collection

Effects of acceleration in the Gz axis on human cardiopulmonary responses to exercise

Antonutto, Guglielmo
Capelli, Carlo
Linnarsson, Dag
Pendergast, David R
Published in European Journal of Applied Physiology. 2011, vol. 111, no. 12, p. 2907-17
Abstract The aim of this paper was to develop a model from experimental data allowing a prediction of the cardiopulmonary responses to steady-state submaximal exercise in varying gravitational environments, with acceleration in the G(z) axis (a (g)) ranging from 0 to 3 g. To this aim, we combined data from three different experiments, carried out at Buffalo, at Stockholm and inside the Mir Station. Oxygen consumption, as expected, increased linearly with a (g). In contrast, heart rate increased non-linearly with a (g), whereas stroke volume decreased non-linearly: both were described by quadratic functions. Thus, the relationship between cardiac output and a (g) was described by a fourth power regression equation. Mean arterial pressure increased with a (g) non linearly, a relation that we interpolated again with a quadratic function. Thus, total peripheral resistance varied linearly with a (g). These data led to predict that maximal oxygen consumption would decrease drastically as a (g) is increased. Maximal oxygen consumption would become equal to resting oxygen consumption when a (g) is around 4.5 g, thus indicating the practical impossibility for humans to stay and work on the biggest Planets of the Solar System.
Keywords AccelerationAdultAstronautsBlood Pressure/physiologyCardiac Output/physiologyExercise/physiologyExercise Test/methodsGravitationHeart/physiologyHeart Rate/physiologyHumansLung/physiologyMaleOxygen Consumption/physiologySpace FlightStroke Volume/physiology
PMID: 21437604
Full text
Article (Published version) (423 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research group Métabolisme énergétique (642)
(ISO format)
BONJOUR, Julien et al. Effects of acceleration in the Gz axis on human cardiopulmonary responses to exercise. In: European Journal of Applied Physiology, 2011, vol. 111, n° 12, p. 2907-17. https://archive-ouverte.unige.ch/unige:25868

225 hits

1 download


Deposited on : 2013-01-23

Export document
Format :
Citation style :