Scientific article
English

When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study

Published inAnnals of internal medicine, vol. 154, no. 8, p. 509-515
Publication date2011
Abstract

Most clinical guidelines recommend that AIDS-free, HIV-infected persons with CD4 cell counts below 0.350 × 10(9) cells/L initiate combined antiretroviral therapy (cART), but the optimal CD4 cell count at which cART should be initiated remains a matter of debate.

Keywords
  • Acquired Immunodeficiency Syndrome/drug therapy/immunology/mortality
  • Anti-Retroviral Agents/administration & dosage/therapeutic use
  • CD4 Lymphocyte Count
  • Cause of Death
  • Developed Countries
  • Disease Progression
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • HIV Infections/drug therapy/immunology/mortality
  • Humans
  • Observation
  • Proportional Hazards Models
  • Prospective Studies
Citation (ISO format)
CAIN, Lauren E et al. When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study. In: Annals of internal medicine, 2011, vol. 154, n° 8, p. 509–515. doi: 10.1059/0003-4819-154-8-201104190-00001
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0003-4819
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Creation13/12/2012 10:28:00
First validation13/12/2012 10:28:00
Update14/03/2023 19:59:05
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