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Scientific article
English

Response of iron overload to deferasirox in rare transfusion-dependent anaemias: equivalent effects on serum ferritin and labile plasma iron for haemolytic or production anaemias

CollaboratorsOzsahin, Ayse Hulya
Published inEuropean journal of haematology, vol. 87, no. 4, p. 338-348
Publication date2011
Abstract

It is widely assumed that, at matched transfusional iron-loading rates, responses to chelation therapy are similar, irrespective of the underlying condition. However, data are limited for rare transfusion-dependent anaemias, and it remains to be elucidated if response differs, depending on whether the anaemia has a primary haemolytic or production mechanism.

Keywords
  • Adolescent
  • Anemia/drug therapy
  • Benzoates/therapeutic use
  • Blood Transfusion
  • Child
  • Child, Preschool
  • Female
  • Ferritins/blood
  • Humans
  • Iron/blood
  • Iron Chelating Agents/therapeutic use
  • Iron Overload
  • Male
  • Triazoles/therapeutic use
Citation (ISO format)
PORTER, John B et al. Response of iron overload to deferasirox in rare transfusion-dependent anaemias: equivalent effects on serum ferritin and labile plasma iron for haemolytic or production anaemias. In: European journal of haematology, 2011, vol. 87, n° 4, p. 338–348. doi: 10.1111/j.1600-0609.2011.01660.x
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0902-4441
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