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Scientific article
English

ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia

Published inPharmacogenomics, vol. 12, no. 10, p. 1493-1501
Publication date2011
Abstract

To examine the safety profile of oseltamivir in children and evaluate the impact of P-glycoprotein polymorphisms on the incidence of neuropsychiatric adverse events (NPAE) in oseltamivir-treated children.

Keywords
  • Adolescent
  • Antiviral Agents/adverse effects/therapeutic use
  • Blood-Brain Barrier/drug effects
  • Capillary Permeability/drug effects/genetics
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Influenza A Virus, H1N1 Subtype
  • Influenza, Human/drug therapy
  • Mental Disorders/chemically induced/genetics
  • Oseltamivir/adverse effects/therapeutic use
  • P-Glycoprotein/genetics
  • Pandemics
  • Polymorphism, Single Nucleotide
Citation (ISO format)
L’HUILLIER, Arnaud et al. ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia. In: Pharmacogenomics, 2011, vol. 12, n° 10, p. 1493–1501. doi: 10.2217/pgs.11.91
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Article (Published version)
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Identifiers
ISSN of the journal1462-2416
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Creation2012/12/17 15:32:00
First validation2012/12/17 15:32:00
Update time2023/03/14 19:58:40
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