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Title

Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer

Authors
Fisch, Urs P
Zehnder, Aina
Hirt, Andreas
Niggli, Felix K
Schlapbach, Luregn J
Ammann, Roland A
Published in Swiss Medical Weekly. 2011, vol. 141, p. w13191
Abstract Mannan-binding lectin (MBL) and MBL-associated serine protease-2 (MASP-2) are two key components of the lectin-pathway of complement-activation. Information on the potential role of lectin-pathway components in carcinogenesis versus immune surveillance of cancer is scarce. This study aimed to determine if serum concentrations of MBL and MASP-2 differ between children with cancer and healthy age-matched controls.
Keywords ChildComplement Pathway, Mannose-Binding LectinEnzyme-Linked Immunosorbent AssayHumansImmunity, InnateMannose-Binding Lectin/bloodMannose-Binding Protein-Associated Serine Proteases/analysisMedical AuditNeoplasms/classificationRetrospective StudiesSwitzerland
Identifiers
PMID: 21528466
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Research group Groupe Ozsahin Ayse Hulya (onco-hémato pédiatrie) (889)
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FISCH, Urs P et al. Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer. In: Swiss Medical Weekly, 2011, vol. 141, p. w13191. https://archive-ouverte.unige.ch/unige:25742

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Deposited on : 2013-01-21

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