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Scientific article
Meta-analysis
Open access
English

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease

Published inArthritis research & therapy, vol. 13, no. 5, R166
Publication date2011
Abstract

T cell abnormalities have been associated with the pathogenesis of systemic sclerosis (SSc). Recently, besides T helper (Th)17 cells, the Th22 subset has been identified in humans. Our purpose was to investigate the pattern of cytokines produced and chemokine-receptors expressed by peripheral blood (PB) Th cells in SSc and healthy donors (HD) focusing on cells producing interleukin (IL)-17 and IL-22 and to identify specific clinical associations.

Citation (ISO format)
TRUCHETET, Marie-Elise et al. Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease. In: Arthritis research & therapy, 2011, vol. 13, n° 5, p. R166. doi: 10.1186/ar3486
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ISSN of the journal1478-6354
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Creation12/13/2012 5:09:00 PM
First validation12/13/2012 5:09:00 PM
Update time03/14/2023 7:58:35 PM
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