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Abnormal hypothalamic response to light in seasonal affective disorder

Vandewalle, Gilles
Hébert, Marc
Beaulieu, Catherine
Richard, Laurence
Daneault, Véronique
Garon, Marie-Lou
Leblanc, Jean
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Published in Biological Psychiatry. 2011, vol. 70, no. 10, p. 954-961
Abstract Vulnerability to the reduction in natural light associated with fall/winter is generally accepted as the main trigger of seasonal affective disorder (SAD), whereas light therapy is a treatment of choice of the disorder. However, the relationship between exposure to light and mood regulation remains unclear. As compared with green light, blue light was shown to acutely modulate emotion brain processing in healthy individuals. Here, we investigated the impact of light on emotion brain processing in patients with SAD and healthy control subjects and its relationship with retinal light sensitivity.
Keywords Acoustic StimulationAdolescentAdultColorElectroretinographyEmotions/physiologyFemaleHumansHypothalamus/blood supply/physiopathologyImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedOxygen/bloodReaction TimeSeasonal Affective Disorder/pathologyYoung Adult
PMID: 21820647
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Article (Published version) (793 Kb) - public document Free access
Research groups Affective sciences
Neuroimagerie du Sommeil et de la Cognition (832)
Neuroscience de l'émotion et dynamiques affectives (NEAD)
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VANDEWALLE, Gilles et al. Abnormal hypothalamic response to light in seasonal affective disorder. In: Biological Psychiatry, 2011, vol. 70, n° 10, p. 954-961. doi: 10.1016/j.biopsych.2011.06.022 https://archive-ouverte.unige.ch/unige:25651

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Deposited on : 2013-01-17

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