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Scientific article
English

Effects of pioglitazone on renal calcium excretion

Published inThe Journal of clinical endocrinology and metabolism, vol. 96, no. 9, p. E1482-1485
Publication date2011
Abstract

Glitazones increase fracture risk in long-term users and in postmenopausal women. Studies have demonstrated deleterious effects of glitazones on bone metabolism. Glitazones also have direct renal tubular effects increasing sodium reabsorption. We hypothesized that glitazones may also regulate renal calcium excretion.

Keywords
  • Calcium/urine
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Hypoglycemic Agents/pharmacology
  • Kidney/drug effects/metabolism
  • Male
  • Middle Aged
  • Parathyroid Hormone/blood
  • Phosphates/urine
  • Sodium, Dietary/metabolism
  • Thiazolidinediones/pharmacology
Citation (ISO format)
ZANCHI, Anne et al. Effects of pioglitazone on renal calcium excretion. In: The Journal of clinical endocrinology and metabolism, 2011, vol. 96, n° 9, p. E1482–1485. doi: 10.1210/jc.2011-0373
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0021-972X
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