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Title

High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets

Authors
Immonen, Riikka
Nabuurs, Christine
Gjinovci, Asllan
Montet, Xavier C R
Published in Diabetes. 2011, vol. 60, no. 11, p. 2853-60
Abstract We studied whether manganese-enhanced high-field magnetic resonance (MR) imaging (MEHFMRI) could quantitatively detect individual islets in situ and in vivo and evaluate changes in a model of experimental diabetes.
Keywords AlgorithmsAnimalsChlorides/administration & dosageContrast Media/administration & dosageDiabetes Mellitus, Type 1/chemically induced/metabolism/pathologyGlucagon/metabolismGlucagon-Secreting Cells/metabolism/pathologyGlucose/administration & dosage/metabolismImage Enhancement/methodsImmunohistochemistryInfusions, IntravenousInjections, IntraperitonealInsulin/metabolismInsulin-Secreting Cells/metabolism/pathologyIslets of Langerhans/metabolism/pathologyMagnetic Resonance ImagingManganese Compounds/administration & dosageMiceMice, Inbred C57BLOrgan SizeStreptozocin/toxicity
Identifiers
PMID: 21926272
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Article (Published version) (2.6 MB) - public document Free access
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Research group Couplage cellulaire et connexines (136)
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LAMPRIANOU, Smaragda et al. High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets. In: Diabetes, 2011, vol. 60, n° 11, p. 2853-60. https://archive-ouverte.unige.ch/unige:25466

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Deposited on : 2013-01-14

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