Presurgical evaluation of epilepsy patients

Gelziniene, Giedre; Endziniene, Milda; Vaiciene, Nerija; Magistris, Michel; Seeck, Margitta

Scientific article

English

Presurgical evaluation of epilepsy patients

Contributors

Gelziniene, Giedre; Endziniene, Milda; Vaiciene, Nerija; Magistris, Michel; Seeck, Margitta

Published in

Medicina, vol. 44, no. 8, p. 585-592

Publication date

2008

Abstract

Epilepsy surgery has been established as an effective treatment in pharmacoresistant focal epilepsies. Most candidates for epilepsy surgery are patients with partial epilepsy syndromes refractory to medical treatment. The curative surgery procedure is resection of the epileptogenic zone; therefore, precise detection of the site responsible for seizure generation is necessary. Modern structural and functional imaging techniques have made presurgical evaluation less invasive and available for a higher number of patients. Video electroencephalography (EEG) monitoring, high-resolution structural and functional imaging techniques are used widely for presurgical evaluation. When noninvasive evaluation is not sufficient for the detection of the epileptogenic zone, invasive EEG monitoring and intracarotid amobarbital test are used. A classical example of a surgically curable epilepsy syndrome is mesial temporal lobe epilepsy with about 70-80% of patients becoming free of seizures after surgery. Results in extratemporal epilepsies are also satisfactory. Despite worldwide expansion during the recent decade, epilepsy surgery remains underutilized. Better understanding of advances in presurgical evaluation should reduce fears of epilepsy surgery and help to select patients who could achieve complete seizure control or significant amelioration after surgery.

UNIGE affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

UNIGE research groups

Epilepsie et Chirurgie (149)

Citation (ISO format)

GELZINIENE, Giedre et al. Presurgical evaluation of epilepsy patients. In: Medicina, 2008, vol. 44, n° 8, p. 585–592.

Article (Accepted version)

Identifiers

PID : unige:2545
PMID : 18791335

Additional URL for this publication

http://medicina.kmu.lt/0808/0808-03e.htm

Journal ISSN

1010-660X

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602downloads

Creation

28/08/2009 12:03:00

First validation

28/08/2009 12:03:00

Update

14/03/2023 15:11:05

Status update

14/03/2023 15:11:04

Last indexation

29/10/2024 11:56:15

Presurgical evaluation of epilepsy patients

Contributors

Published in

Publication date

Abstract

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

Main files (1)

Identifiers

Additional URL for this publication

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation