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Resting functional connectivity in patients with brain tumors in eloquent areas

Martino, Juan
Honma, Susanne M
Findlay, Anne M
Owen, Julia P
Kirsch, Heidi E
Berger, Mitchel S
Nagarajan, Srikantan S
Published in Annals of Neurology. 2011, vol. 69, no. 3, p. 521-32
Abstract Resection of brain tumors adjacent to eloquent areas represents a challenge in neurosurgery. If maximal resection is desired without inducing postoperative neurological deficits, a detailed knowledge of the functional topography in and around the tumor is crucial. The aim of the present work is to evaluate the value of preoperative magnetoencephalography (MEG) imaging of functional connectivity to predict the results of intraoperative electrical stimulation (IES) mapping, the clinical gold standard for neurosurgical localization of functional areas.
Keywords AdultAgedBrain MappingBrain Neoplasms/pathology/physiopathologyCerebral Cortex/pathology/physiopathologyElectric StimulationFemaleGlioma/pathology/physiopathologyHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMagnetoencephalographyMaleMiddle AgedNerve Net/pathology/physiopathologyPreoperative PeriodStatistics, Nonparametric
PMID: 21400562
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Research group Neuroréhabilitation assistée par imagerie (910)
Project FNS: 320030-129679
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MARTINO, Juan et al. Resting functional connectivity in patients with brain tumors in eloquent areas. In: Annals of Neurology, 2011, vol. 69, n° 3, p. 521-32. doi: 10.1002/ana.22167 https://archive-ouverte.unige.ch/unige:25401

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Deposited on : 2013-01-11

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