Scientific article

The electroencephalographic fingerprint of sleep is genetically determined: a twin study

Published inAnnals of neurology, vol. 64, no. 4, p. 455-460
Publication date2008

Humans have an individual profile of the electroencephalographic power spectra at the 8 to 16 Hz frequency during non-rapid eye movement sleep that is stable over time and resistant to experimental perturbations. We tested the hypothesis that this electroencephalographic "fingerprint" is genetically determined, by recording 40 monozygotic and dizygotic twins during baseline and recovery sleep after prolonged wakefulness. We show a largely greater similarity within monozygotic than dizygotic pairs, resulting in a heritability estimate of 96%, not influenced by sleep need and intensity. If replicated, these results will establish the electroencephalographic profile during sleep as one of the most heritable traits of humans.

  • Adult
  • Electroencephalography
  • Female
  • Humans
  • Male
  • Polysomnography
  • Sleep/genetics
  • Twins, Dizygotic/physiology
  • Twins, Monozygotic/physiology
  • Wakefulness/genetics
  • Young Adult
Citation (ISO format)
DE GENNARO, Luigi et al. The electroencephalographic fingerprint of sleep is genetically determined: a twin study. In: Annals of neurology, 2008, vol. 64, n° 4, p. 455–460. doi: 10.1002/ana.21434
Main files (1)
Article (Accepted version)
ISSN of the journal0364-5134

Technical informations

Creation08/28/2009 11:07:00 AM
First validation08/28/2009 11:07:00 AM
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