en
Scientific article
English

Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections

Published inJournal of hepatology, vol. 55, no. 1, p. 53-60
Publication date2011
Abstract

Chronic microbial infections are frequently associated with B-cell activation and polyclonal proliferation, potentially leading to autoimmunity and lymphoproliferative disorders. We assessed B-cell phenotype and function in chronic hepatitis B (HBV) and chronic hepatitis C (HCV) virus infection.

Keywords
  • Adolescent
  • Adult
  • Aged
  • B-Lymphocytes/immunology/pathology
  • Base Sequence
  • Case-Control Studies
  • Cell Differentiation
  • Cell Proliferation
  • Female
  • Hepacivirus/genetics
  • Hepatitis B, Chronic/immunology/pathology
  • Hepatitis C, Chronic/immunology/pathology/virology
  • Humans
  • Immunophenotyping
  • Lymphocyte Activation
  • Male
  • Middle Aged
  • RNA, Viral/analysis/genetics
  • Young Adult
Citation (ISO format)
OLIVIERO, Barbara et al. Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections. In: Journal of hepatology, 2011, vol. 55, n° 1, p. 53–60. doi: 10.1016/j.jhep.2010.10.016
Main files (1)
Article (Published version)
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Identifiers
ISSN of the journal0168-8278
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Creation10/24/2012 4:38:00 PM
First validation10/24/2012 4:38:00 PM
Update time03/14/2023 7:55:02 PM
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