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Scientific article
Open access
English

Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis

Published inBMC gastroenterology, vol. 11, 115
Publication date2011
Abstract

Alcoholic steatohepatitis (ASH) is a serious complication of alcoholic liver disease. The diagnosis of ASH requires the association of steatosis, evidence of hepatocellular injury with ballooning degeneration, and polynuclear neutrophil infiltration on liver biopsy. Whether these lesions, in addition to other histological features observed in liver tissue specimens, have prognostic significance is unclear.

Keywords
  • Adult
  • Age Factors
  • Aged
  • Bilirubin/blood
  • Biopsy, Fine-Needle
  • Cholestasis, Intrahepatic/complications/mortality/pathology
  • Cohort Studies
  • Fatty Liver, Alcoholic/complications/mortality/pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Liver/pathology
  • Liver Cirrhosis, Alcoholic/complications/mortality/pathology
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Prognosis
  • Proportional Hazards Models
  • Severity of Illness Index
  • Survival Rate
Citation (ISO format)
SPAHR, Laurent François Joséph et al. Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis. In: BMC gastroenterology, 2011, vol. 11, p. 115. doi: 10.1186/1471-230X-11-115
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1471-230X
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228downloads

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