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Sevoflurane and desflurane protect cholinergic-induced bronchoconstriction of hyperreactive airways in rabbits

Published inCanadian journal of anaesthesia, vol. 58, no. 11, p. 1007-1015
Publication date2011
Abstract

The potential of desflurane to alter respiratory mechanics in the presence of bronchial hyperresponsiveness (BHR) is still a subject of debate. Accordingly, we evaluated the bronchoprotective potential of desflurane compared with sevoflurane following cholinergic lung constriction in rabbits with normal and hyperreactive airways.

Keywords
  • Anesthetics, Inhalation/pharmacology
  • Animals
  • Bronchial Hyperreactivity/physiopathology
  • Bronchoconstriction/drug effects
  • Isoflurane/analogs & derivatives/pharmacology
  • Methacholine Chloride/pharmacology
  • Methyl Ethers/pharmacology
  • Muscarinic Agonists/pharmacology
  • Rabbits
Citation (ISO format)
MYERS, Carole et al. Sevoflurane and desflurane protect cholinergic-induced bronchoconstriction of hyperreactive airways in rabbits. In: Canadian journal of anaesthesia, 2011, vol. 58, n° 11, p. 1007–1015. doi: 10.1007/s12630-011-9578-3
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Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN0832-610X
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Creation11/14/2012 8:26:00 PM
First validation11/14/2012 8:26:00 PM
Update time01/10/2025 11:02:32 AM
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