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Title

Persistence of recipient-type endothelium after allogeneic hematopoietic stem cell transplantation

Authors
Mueller, Regula J
Stussi, Georg
Nikolic, Milica
Soldini, Davide
Halter, Jörg
Meyer-Monard, Sandrine
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Published in Haematologica. 2011, vol. 96, no. 1, p. 119-27
Abstract The possibility that allogeneic hematopoietic stem cell transplantation performed across the ABO blood group-barrier is associated with an increase of graft-versus-host disease, in particular endothelial damage, has not been elucidated so far. For this reason, we investigated the level of endothelial cell chimerism after allogeneic hematopoietic stem cell transplantation in order to delineate the role of hematopoietic stem cells in endothelial replacement.
Keywords ABO Blood-Group System/metabolismAdultBlood Group IncompatibilityChimerismChromosomes, Human, X/geneticsChromosomes, Human, Y/geneticsEndothelium, Vascular/physiologyGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunoenzyme TechniquesIn Situ Hybridization, FluorescenceMiddle AgedNeovascularization, PathologicProspective StudiesTandem Repeat SequencesTissue DonorsTransplantation, HomologousYoung AdultVon Willebrand Factor/metabolism
Identifiers
PMID: 20934999
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Research group Groupe Seebach Jorg Dieter (transplantation et immunologie) (856)
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MUELLER, Regula J et al. Persistence of recipient-type endothelium after allogeneic hematopoietic stem cell transplantation. In: Haematologica, 2011, vol. 96, n° 1, p. 119-27. https://archive-ouverte.unige.ch/unige:25119

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Deposited on : 2013-01-08

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