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Title

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Authors
Trotter, Caroline L.
McVernon, Jodie
Ramsay, Mary E.
Whitney, Cynthia G.
Mulholland, E Kim
Goldblatt, David
Hombach, Joachim
Kieny, Marie-Paule
CollaborationWith : Siegrist, Claire-Anne
Published in Vaccine. 2008, vol. 26, no. 35, p. 4434-45
Abstract Conjugate vaccines exist that offer protection against disease caused by Haemophilus influenzae type b (Hib), and selected serogroups/serotypes of Neisseria meningitidis and Streptococcus pneumoniae. These vaccines are not only able to prevent serious disease, but they also provide protection against asymptomatic carriage. The resulting herd immunity effects have been striking, and have played an important role in the public health success of conjugate vaccination programmes. The aim of this paper is to review the state of the current evidence on conjugate vaccines and to identify important areas for further study, in order to inform the debate regarding the best use of these vaccines.
Keywords Carrier State/prevention & controlHaemophilus Infections/prevention & controlHaemophilus Vaccines/immunologyHaemophilus influenzae type b/immunologyHumansMeningococcal Infections/prevention & controlMeningococcal Vaccines/immunologyNeisseria meningitidis/immunologyPneumococcal Infections/prevention & controlPneumococcal Vaccines/immunologyStreptococcus pneumoniae/immunologyVaccines, Conjugate
Identifiers
PMID: 18617296
Full text
Article (Author postprint) (241 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Centre de Vaccinologie et d'Immunologie néonatale (177)
Citation
(ISO format)
TROTTER, Caroline L. et al. Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae. In: Vaccine, 2008, vol. 26, n° 35, p. 4434-45. https://archive-ouverte.unige.ch/unige:2506

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Deposited on : 2009-08-27

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