The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice
Contributeurs/tricesMcCall, Michael; Toso, Christian; Emamaullee, Juliet; Pawlick, Rena; Edgar, Ryan; Davis, Joy; Maciver, Allison; Kin, Tatsuya; Arch, Robert; Shapiro, A M James
Publié dansSurgery, vol. 150, no. 1, p. 48-55
Date de publication2011
Résumé
Mots-clés
- Animals
- Apoptosis/drug effects
- Blood Glucose/metabolism
- Caspases/antagonists & inhibitors
- Cysteine Proteinase Inhibitors/pharmacology
- Diabetes Mellitus, Experimental/blood/drug therapy/surgery
- Glucose Tolerance Test
- Graft Enhancement, Immunologic/methods
- Graft Survival/drug effects
- Humans
- Islets of Langerhans Transplantation/pathology/physiology
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Pentanoic Acids/pharmacology
- Transplantation, Heterologous
- Transplantation, Isogeneic
Structure d'affiliation
Groupe de recherche
Citation (format ISO)
MCCALL, Michael et al. The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice. In: Surgery, 2011, vol. 150, n° 1, p. 48–55. doi: 10.1016/j.surg.2011.02.023
Fichiers principaux (1)
Article (Published version)
Identifiants
- PID : unige:24964
- DOI : 10.1016/j.surg.2011.02.023
- PMID : 21596412
ISSN du journal0039-6060