UNIGE document Scientific Article
previous document  unige:2493  next document
add to browser collection
Title

MAPRes: Mining association patterns among preferred amino acid residues in the vicinity of amino acids targeted for post-translational modifications

Authors
Ahmad, Ishtiaq
Qazi, Wajahat M.
Khurshid, Ahmed
Ahmad, Munir
Khawaja, Iffat
Choudhary, M Iqbal
Shakoori, Abdul R.
show hidden authors show all authors [1 - 9]
Published in Proteomics. 2008, vol. 8, no. 10, p. 1954-8
Abstract Post-translational modification (PTM) of a protein is an important event in regulating cellular functions. An algorithm, MAPRes, has been developed for mining associations among PTM sites and the preferred amino acids in their vicinity. The algorithm has been implemented to O-glycosylation and O-phosphorylation data (phosphorylated/glycosylated Ser/Thr/Tyr). The association patterns mined by MAPRes demonstrate significant correlations and the results are in conformity with the existing methods. These association rules/patterns will be helpful in predicting the sequences/motifs involved for specific PTMs in proteins.
Keywords AlgorithmsAmino Acids/metabolismGlycosylationPhosphorylationProtein Processing, Post-Translational
Identifiers
PMID: 18491291
Full text
Structures
Citation
(ISO format)
AHMAD, Ishtiaq et al. MAPRes: Mining association patterns among preferred amino acid residues in the vicinity of amino acids targeted for post-translational modifications. In: Proteomics, 2008, vol. 8, n° 10, p. 1954-8. https://archive-ouverte.unige.ch/unige:2493

221 hits

1 download

Update

Deposited on : 2009-08-25

Export document
Format :
Citation style :