Proteomic analysis reveals that apolipoprotein A1 levels are decreased in patients with Budd-Chiari syndrome

Talens, Simone; Hoekstra, Jildou; Dirkx, Steffen P G; Darwish Murad, Sarwa; Trebicka, Jonel; Elias, Elwyn; Primignani, Massimo; García-Pagán, Juan-Carlos; Valla, Dominique; Janssen, Harry L A; Leebeek, Frank W G; Rijken, Dingeman C; Langlet, P; Lasser, L; Plessier, A; Condat, B; Bahr, M; Heller, J; Rossle, M; Fabris, F; Rosendaal, FR; Miranda, H; Hernandez-Guerra, M; Raffa, S; Lozano, R; Hadengue, Antoine; Morard, Isabelle; Mentha, Gilles; Eapen, CE

doi:10.1016/j.jhep.2010.08.026

Scientific article

English

Proteomic analysis reveals that apolipoprotein A1 levels are decreased in patients with Budd-Chiari syndrome

Published inJournal of hepatology, vol. 54, no. 5, p. 908-914

Publication date2011

Abstract

Budd-Chiari syndrome (BCS) is a rare vascular liver disorder caused by thrombosis of the hepatic veins. In some patients, no known thrombophilic factor can be identified. This study aimed to identify novel factors that might play a role in thrombosis in BCS-patients by using a proteomic approach.

Keywords

Apolipoprotein A-I/blood
Budd-Chiari Syndrome/blood/complications
Case-Control Studies
Cholesterol, HDL/blood
Cohort Studies
Electrophoresis, Gel, Two-Dimensional
Hepatic Veins
Humans
Proteomics
Thrombosis/blood/etiology

Affiliation entities

Research groups

Hépatologie chirurgicale (327)

Citation (ISO format)

TALENS, Simone et al. Proteomic analysis reveals that apolipoprotein A1 levels are decreased in patients with Budd-Chiari syndrome. In: Journal of hepatology, 2011, vol. 54, n° 5, p. 908–914. doi: 10.1016/j.jhep.2010.08.026

Article (Published version)

Identifiers

PID : unige:24894
DOI : 10.1016/j.jhep.2010.08.026
PMID : 21145806

ISSN of the journal0168-8278

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Proteomic analysis reveals that apolipoprotein A1 levels are decreased in patients with Budd-Chiari syndrome

Budd-Chiari syndrome (BCS) is a rare vascular liver disorder caused by thrombosis of the hepatic veins. In some patients, no known thrombophilic factor can be identified. This study aimed to identify novel factors that might play a role in thrombosis in BCS-patients by using a proteomic approach.

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