en
Scientific article
Meta-analysis
English

Immune monitoring of pancreatic islet graft: towards a better understanding, detection and treatment of harmful events

Published inExpert opinion on biological therapy, vol. 11, no. 1, p. 55-66
Publication date2011
Abstract

Long-term clinical outcomes of islet transplantation are hampered by rejection and recurrence of autoimmunity, which lead to a gradual decrease in islet function usually taking place over the first five years after transplantation. An accurate monitoring strategy could allow for the detection and treatment of harmful immune events, potentially resulting in higher rates of insulin-independence.

Keywords
  • Autoantibodies/biosynthesis/immunology
  • Diabetes Mellitus, Type 1/immunology/surgery
  • Humans
  • Immunity, Innate
  • Islets of Langerhans Transplantation/adverse effects/immunology
  • Monitoring, Physiologic
  • Postoperative Period
  • T-Lymphocytes, Cytotoxic/immunology
Citation (ISO format)
LACOTTE, Stéphanie et al. Immune monitoring of pancreatic islet graft: towards a better understanding, detection and treatment of harmful events. In: Expert opinion on biological therapy, 2011, vol. 11, n° 1, p. 55–66. doi: 10.1517/14712598.2011.536530
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1471-2598
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