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Title

Immune monitoring of pancreatic islet graft: towards a better understanding, detection and treatment of harmful events

Authors
Shapiro, Am James
Published in Expert Opinion on Biological Therapy. 2011, vol. 11, no. 1, p. 55-66
Abstract Long-term clinical outcomes of islet transplantation are hampered by rejection and recurrence of autoimmunity, which lead to a gradual decrease in islet function usually taking place over the first five years after transplantation. An accurate monitoring strategy could allow for the detection and treatment of harmful immune events, potentially resulting in higher rates of insulin-independence.
Keywords Autoantibodies/biosynthesis/immunologyDiabetes Mellitus, Type 1/immunology/surgeryHumansImmunity, InnateIslets of Langerhans Transplantation/adverse effects/immunologyMonitoring, PhysiologicPostoperative PeriodT-Lymphocytes, Cytotoxic/immunology
Identifiers
PMID: 21073277
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Article (Published version) (373 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Transplantation et hépatologie (905)
La transplantation d'îlots de Langerhans (623)
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(ISO format)
LACOTTE, Stéphanie et al. Immune monitoring of pancreatic islet graft: towards a better understanding, detection and treatment of harmful events. In: Expert Opinion on Biological Therapy, 2011, vol. 11, n° 1, p. 55-66. https://archive-ouverte.unige.ch/unige:24891

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Deposited on : 2013-01-03

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