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Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability

Bertolotto, Maria
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Published in European heart journal. 2011, vol. 32, no. 4, p. 412-21
Abstract Anti-Apolipoprotein A-1 auto-antibodies (anti-ApoA-1 IgG) represent an emerging prognostic cardiovascular marker in patients with myocardial infarction or autoimmune diseases associated with high cardiovascular risk. The potential relationship between anti-ApoA-1 IgG and plaque vulnerability remains elusive. Thus, we aimed to investigate the role of anti-ApoA-1 IgG in plaque vulnerability.
Keywords AgedAnimalsApolipoprotein A-I/immunologyAutoantibodies/bloodBiological Markers/bloodCarotid Artery, InternalCarotid Stenosis/immunologyCohort StudiesCollagen/metabolismCytokines/metabolismEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin G/bloodMaleMatrix Metalloproteinase 9/metabolismMiceMice, Inbred C57BLPlaque, Atherosclerotic/immunology
PMID: 21224292
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Research groups Chimie et protéomique clinique (270)
Etude de l'activation des monocytes/macrophages et des polynucléaires neutrophiles (779)
Groupe Bouras Constantin (neuropsychiatrie) (1)
L'athérosclérose et ses complications cliniques (591)
Traits génétiques complexes (901)
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MONTECUCCO, Fabrizio et al. Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability. In: European heart journal, 2011, vol. 32, n° 4, p. 412-21. doi: 10.1093/eurheartj/ehq521 https://archive-ouverte.unige.ch/unige:24776

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Deposited on : 2012-12-19

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