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Scientific article
English

Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability

Published inEuropean heart journal, vol. 32, no. 4, p. 412-421
Publication date2011
Abstract

Anti-Apolipoprotein A-1 auto-antibodies (anti-ApoA-1 IgG) represent an emerging prognostic cardiovascular marker in patients with myocardial infarction or autoimmune diseases associated with high cardiovascular risk. The potential relationship between anti-ApoA-1 IgG and plaque vulnerability remains elusive. Thus, we aimed to investigate the role of anti-ApoA-1 IgG in plaque vulnerability.

Keywords
  • Aged
  • Animals
  • Apolipoprotein A-I/immunology
  • Autoantibodies/blood
  • Biological Markers/blood
  • Carotid Artery, Internal
  • Carotid Stenosis/immunology
  • Cohort Studies
  • Collagen/metabolism
  • Cytokines/metabolism
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G/blood
  • Male
  • Matrix Metalloproteinase 9/metabolism
  • Mice
  • Mice, Inbred C57BL
  • Plaque, Atherosclerotic/immunology
Citation (ISO format)
MONTECUCCO, Fabrizio et al. Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability. In: European heart journal, 2011, vol. 32, n° 4, p. 412–421. doi: 10.1093/eurheartj/ehq521
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Article (Published version)
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Identifiers
ISSN of the journal0195-668X
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Update time03/14/2023 5:48:11 PM
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