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Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability |
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Published in | European heart journal. 2011, vol. 32, no. 4, p. 412-21 | |
Abstract | Anti-Apolipoprotein A-1 auto-antibodies (anti-ApoA-1 IgG) represent an emerging prognostic cardiovascular marker in patients with myocardial infarction or autoimmune diseases associated with high cardiovascular risk. The potential relationship between anti-ApoA-1 IgG and plaque vulnerability remains elusive. Thus, we aimed to investigate the role of anti-ApoA-1 IgG in plaque vulnerability. | |
Keywords | Aged — Animals — Apolipoprotein A-I/immunology — Autoantibodies/blood — Biological Markers/blood — Carotid Artery, Internal — Carotid Stenosis/immunology — Cohort Studies — Collagen/metabolism — Cytokines/metabolism — Enzyme-Linked Immunosorbent Assay — Female — Humans — Immunoglobulin G/blood — Male — Matrix Metalloproteinase 9/metabolism — Mice — Mice, Inbred C57BL — Plaque, Atherosclerotic/immunology | |
Identifiers | PMID: 21224292 | |
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Research groups | Chimie et protéomique clinique (270) Etude de l'activation des monocytes/macrophages et des polynucléaires neutrophiles (779) Groupe Bouras Constantin (neuropsychiatrie) (1) L'athérosclérose et ses complications cliniques (591) Traits génétiques complexes (901) | |
Citation (ISO format) | MONTECUCCO, Fabrizio et al. Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability. In: European heart journal, 2011, vol. 32, n° 4, p. 412-21. doi: 10.1093/eurheartj/ehq521 https://archive-ouverte.unige.ch/unige:24776 |