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Scientific article
English

Absolute Configuration and Enantiodifferentiation of a Hemicryptophane Incorporating an Azaphosphatrane Moiety

Published inChirality, vol. 24, no. 12, p. 1077-1081
Publication date2012
Abstract

The hemicryptophane racemate (±)-M-1, P-1 was optically resolved by semipreparative HPLC on Chiralpak IC column. The absolute configuration of each isolated enantiomer was established from the analysis of their electronic circular dichroism spectra. Enantiodifferentiation of the chiral cationic cage (±)-M-1, P-1 was evidenced in solution using Δ-TRISPHAT as chiral solvating agent, and the diastereomeric associations were observed in 1H and 31P NMR spectra.

Keywords
  • Hemicryptophane
  • Chiral separation
  • Absolute configuration
  • Chiroptical properties
  • TRISPHAT
  • Chiral solvating agent
Citation (ISO format)
PAYET, Elina et al. Absolute Configuration and Enantiodifferentiation of a Hemicryptophane Incorporating an Azaphosphatrane Moiety. In: Chirality, 2012, vol. 24, n° 12, p. 1077–1081. doi: 10.1002/chir.22100
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Article (Published version)
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ISSN of the journal0899-0042
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Creation11/30/2012 11:52:00 AM
First validation11/30/2012 11:52:00 AM
Update time03/14/2023 5:46:20 PM
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