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Article scientifique
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Accès libre
Anglais

Predicting the pathogen of diabetic toe osteomyelitis by two consecutive ulcer cultures with bone contact

Collection
  • Open Access - Licence nationale Springer
Date de publication2011
Résumé

In this study, we investigate the accuracy of two consecutive ulcer cultures with bone contact compared to bone biopsy for the diagnosis of diabetic toe osteomyelitis. The same nurse and orthopaedic surgeon obtained all samples: sample A-1: bone contact swabbing through the ulcer; sample A-2: a second culture swabbing from the bone surface within 24 h; sample B: surgical bone biopsy in the operating theatre. The kappa statistic measure between samples A-1 and A-2 (bone contact swabs) indicated 82.35% agreement. The sensitivity, specificity, positive and negative predictive values of the two samples A compared to B were 96%, 79%, 92% and 88%, respectively, for the causative pathogen. These results were similar with prior antibiotic treatment, discordant bone surface swabs or with monomicrobial infections. As a conclusion, two consecutive diabetic toe cultures with bone contact accurately predict the pathogen of diabetic toe osteomyelitis in 90% of cases.

Mots-clés
  • Aged
  • Bacterial Infections/diagnosis
  • Bacteriological Techniques/methods
  • Biopsy
  • Diabetes Complications/microbiology
  • Humans
  • Osteomyelitis/microbiology
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Skin Ulcer/microbiology
  • Specimen Handling/methods
  • Toes/microbiology/pathology
Citation (format ISO)
BERNARD, Louis et al. Predicting the pathogen of diabetic toe osteomyelitis by two consecutive ulcer cultures with bone contact. In: European journal of clinical microbiology & infectious diseases, 2011, vol. 30, n° 2, p. 279–281. doi: 10.1007/s10096-010-1078-9
Fichiers principaux (1)
Article (Published version)
accessLevelPublic
Identifiants
ISSN du journal0934-9723
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189téléchargements

Informations techniques

Création22/10/2012 16:03:00
Première validation22/10/2012 16:03:00
Heure de mise à jour14/03/2023 17:45:56
Changement de statut14/03/2023 17:45:56
Dernière indexation16/01/2024 00:34:20
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