UNIGE document Scientific Article - Comment
previous document  unige:24170  next document
add to browser collection
Title

A sweet twist gets Bacillus into shape

Authors
Published in Molecular Microbiology. 2011, vol. 80, no. 2, p. 283-5
Abstract A protective organelle that is essential for viability under most conditions, the cell wall is a dynamic structure that is continuously remodelled with the growth of the bacterial cell. Because the cell wall also moulds the bacterium, the mechanisms of cell wall homeostasis can be deciphered using cell shape as a convenient proxy. In this issue of Molecular Microbiology, Foulquier et al. illuminate a connection between cell shape regulation and metabolism in Bacillus subtilis. They find that the putative NAD(P)-binding enzyme YvcK organizes into helical subcellular structures that exert shape control by directing the cell wall biosynthetic enzyme PBP1 along the cell cylinder and to the septum, a function shared with the MreB actin cytoskeleton. Unlike MreB, however, the role of YvcK in cell shape control is manifested only on certain carbon sources, presumably by way of a previously unknown metabolic feed that taps into cell morphogenesis.
Keywords Bacillus subtilis/cytology/growth & development/metabolismBacterial Proteins/genetics/metabolismCell Wall/metabolismGluconeogenesisModels, Biological
Identifiers
PMID: 21371139
Full text
Article (Published version) (148 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Régulation du cycle cellulaire dans C.crescentus, une bactérie asymétrique (895)
Citation
(ISO format)
MIGNOLET, Johann, VIOLLIER, Patrick. A sweet twist gets Bacillus into shape. In: Molecular Microbiology, 2011, vol. 80, n° 2, p. 283-5. https://archive-ouverte.unige.ch/unige:24170

185 hits

0 download

Update

Deposited on : 2012-11-21

Export document
Format :
Citation style :