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Central nervous system regulation of adipocyte metabolism

Nogueiras, Rubén
Wilson, Hilary
Tschöp, Matthias H.
Published in Regulatory Peptides. 2008, vol. 149, no. 1-3, p. 26-31
Abstract The white adipose tissue was initially largely known only as an energy storage tissue. It is now well recognized that white adipose tissue is a major endocrine and secretory organ, which releases a wide range of protein signals and factors termed adipokines. The regulation of adipocyte metabolism is an important factor for the understanding of obesity, and some mechanisms are still unknown. Many homeostatic processes, including appetite and food intake, are controlled by neuroendocrine circuits involving the central nervous system. There is substantial evidence demonstrating that the central nervous system also directly regulates adipocyte metabolism. In this review, we discuss the central actions of some peptides with an important role in energy balance regulation on adipocyte metabolism and the physiological relevance of these actions.
Keywords Adipocytes/physiologyAnimalsCentral Nervous System/metabolismHumansModels, Biological
PMID: 18453013
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Research group Homéostasie métabolique (649)
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NOGUEIRAS, Rubén et al. Central nervous system regulation of adipocyte metabolism. In: Regulatory Peptides, 2008, vol. 149, n° 1-3, p. 26-31. doi: 10.1016/j.regpep.2007.09.034 https://archive-ouverte.unige.ch/unige:2385

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Deposited on : 2009-08-10

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